I recently tried larger-than-normal methylfolate supplements. I had known that my genes caused problems with processing folate (MTHFR T\/T), but hadn’t noticed any effects from supplementing at 800mcg\/day.<\/p>\n
Due to a report that several milligrams\/day helped with depression, I changed from 400mcg\/day to 2mg\/day. I felt like my mind started working better within hours (although I haven’t seen much change in behavior). I saw a clear and large improvement in my heart rate variability starting after one day.<\/p>\n
I’ve experimented for 5 weeks randomly altering my dose from 1 to 3 mg\/day. On the week when I switched from 3 to 1 mg, my mood slowly got worse. I felt much better withing hours of switching back to 3 mg. I haven’t noticed any clear difference between 2 and 3mg.<\/p>\n","protected":false},"excerpt":{"rendered":"
I recently tried larger-than-normal methylfolate supplements. I had known that my genes caused problems with processing folate (MTHFR T\/T), but hadn’t noticed any effects from supplementing at 800mcg\/day. Due to a report that several milligrams\/day helped with depression, I changed from 400mcg\/day to 2mg\/day. I felt like my mind started working better within hours (although […]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"footnotes":"","jetpack_publicize_message":"","jetpack_is_tweetstorm":false,"jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":false,"jetpack_social_options":{"image_generator_settings":{"template":"highway","enabled":false}}},"categories":[29],"tags":[108],"class_list":["post-1018","post","type-post","status-publish","format-standard","hentry","category-health","tag-diet"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/s80O1l-folate","_links":{"self":[{"href":"https:\/\/bayesianinvestor.com\/blog\/index.php\/wp-json\/wp\/v2\/posts\/1018","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bayesianinvestor.com\/blog\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/bayesianinvestor.com\/blog\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/bayesianinvestor.com\/blog\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/bayesianinvestor.com\/blog\/index.php\/wp-json\/wp\/v2\/comments?post=1018"}],"version-history":[{"count":1,"href":"https:\/\/bayesianinvestor.com\/blog\/index.php\/wp-json\/wp\/v2\/posts\/1018\/revisions"}],"predecessor-version":[{"id":1019,"href":"https:\/\/bayesianinvestor.com\/blog\/index.php\/wp-json\/wp\/v2\/posts\/1018\/revisions\/1019"}],"wp:attachment":[{"href":"https:\/\/bayesianinvestor.com\/blog\/index.php\/wp-json\/wp\/v2\/media?parent=1018"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/bayesianinvestor.com\/blog\/index.php\/wp-json\/wp\/v2\/categories?post=1018"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/bayesianinvestor.com\/blog\/index.php\/wp-json\/wp\/v2\/tags?post=1018"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}